Related Experiment Video

Updated: Jun 23, 2026

Site-Directed Mutagenesis for In Vitro and In Vivo Experiments Exemplified with RNA Interactions in Escherichia Coli
07:04

Site-Directed Mutagenesis for In Vitro and In Vivo Experiments Exemplified with RNA Interactions in Escherichia Coli

Published on: February 5, 2019

Mapping structural perturbations in Escherichia coli aspartate transcarbamylase by medium resolution hydrogen

D S Burz, N M Allewell

    Biophysical Journal
    |May 12, 2009
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
    14:06

    Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays

    Published on: November 12, 2012

    Synthesizing Amino Acids Modified with Reactive Carbonyls in Silico to Assess Structural Effects Using Molecular Dynamics Simulations
    05:57

    Synthesizing Amino Acids Modified with Reactive Carbonyls in Silico to Assess Structural Effects Using Molecular Dynamics Simulations

    Published on: April 26, 2024

    Related Experiment Videos

    Last Updated: Jun 23, 2026

    Site-Directed Mutagenesis for In Vitro and In Vivo Experiments Exemplified with RNA Interactions in Escherichia Coli
    07:04

    Site-Directed Mutagenesis for In Vitro and In Vivo Experiments Exemplified with RNA Interactions in Escherichia Coli

    Published on: February 5, 2019

    Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
    14:06

    Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays

    Published on: November 12, 2012

    Synthesizing Amino Acids Modified with Reactive Carbonyls in Silico to Assess Structural Effects Using Molecular Dynamics Simulations
    05:57

    Synthesizing Amino Acids Modified with Reactive Carbonyls in Silico to Assess Structural Effects Using Molecular Dynamics Simulations

    Published on: April 26, 2024

    Related Concept Videos

    Allosteric Proteins-ATCase01:19

    Allosteric Proteins-ATCase

    Binding sites linkages can regulate a protein's function.  For example, enzyme activity is often regulated through a feedback mechanism where the end product of the biochemical process serves as an inhibitor.
    Aspartate transcarbamoylase (ATCase) is a cytosolic enzyme that catalyzes the condensation of L-aspartate and carbamoyl phosphate to  N-carbamoyl-L-aspartate. This reaction is the first step in pyrimidine biosynthesis. UTP and CTP, the end products of the pyrimidine synthesis pathway,...
    Mismatch Repair01:20

    Mismatch Repair

    Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
    The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
    The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...

    Articles linked to this work by shared authors, journal, and citation graph.

    Negative cooperativity regulates ligand activation of DIAPH1 and other diaphanous related formins.

    Communications biology·2025

    Preliminary analysis of amphibian red cell M ferritin in a novel tetragonal unit cell.

    Acta crystallographica. Section D, Biological crystallography·2004

    The clinically variable R40H mutant ornithine carbamoyltransferase shows cytosolic degradation of the precursor protein in CHO cells.

    Journal of inherited metabolic disease·2002

    Crystallization and preliminary X-ray crystallographic studies of wild-type human ornithine transcarbamylase and two naturally occurring mutants at position 277.

    Acta crystallographica. Section D, Biological crystallography·2001

    Human ornithine transcarbamylase: crystallographic insights into substrate recognition and conformational changes.

    The Biochemical journal·2001

    Isolation of mutations that disrupt cooperative DNA binding by the Drosophila bicoid protein.

    Journal of molecular biology·2000

    Label-Free Microrefractometry of Interfacial Processes Using Fluorescent Smart Coverslips.

    Biophysical journal·2026

    Spatiotemporal 4D Whole-cell Modeling of a Minimal Autotroph Reveals Central Carbon Metabolism Regulated Locally by Protein Megacomplexes via Post-translational Modifications under Light Disturbance.

    Biophysical journal·2026

    Conformational ensembles of flexible multidomain proteins: How close are we to accurate and reliable predictions?

    Biophysical journal·2026

    Constant-pH molecular dynamics simulations of closed and open states of a proton-gated ion channel.

    Biophysical journal·2026

    Single-Molecule Force Spectroscopy Reveals a High-Force Requirement for Dissociation of Integrin Transmembrane Domains.

    Biophysical journal·2026

    The transmembrane domain regulates the kinetics of the SARS-CoV-2 spike conformational transition.

    Biophysical journal·2026

    NUCB2/Nesfatin-1 Couples Cholesterol Biosynthesis to Keratinocyte Migration to Accelerate Re-Epithelialisation in Cutaneous Wound Repair.

    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society·2026

    A Streamlined Workflow for the Isolation of Bovine Satellite Cells From Muscle Tissue.

    Biology of the cell·2026

    Constructing highly efficient hybrid structured Ce-V2O5@PPy as a bifunctional electrocatalyst for overall water splitting.

    RSC advances·2026

    Porous sheet-like carbon nitride with high porosity for efficient visible-light-driven hydrogen evolution reaction.

    RSC advances·2026

    Replacing of Cysteine with Selenocysteine: Biochemical Considerations, Computational Modeling, and Protein Engineering Applications.

    Methods in molecular biology (Clifton, N.J.)·2026

    Generation of Xenopus Transgenic Lines Using I-SceI.

    Methods in molecular biology (Clifton, N.J.)·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us