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Related Concept Videos

Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
Atomic Force Microscopy01:08

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
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The probe is regarded as the heart of any AFM setup and comprises the...

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Related Experiment Video

Updated: Jun 23, 2026

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy
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Published on: February 27, 2015

Attaching molecules to surfaces for scanning probe microscopy

D Keller1, C Bustamante

  • 1Department of Chemistry, University of New Mexico, Albuquerque, New Mexico 87131.

Biophysical Journal
|May 12, 2009
PubMed
Summary

No abstract available in PubMed .

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