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Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers
Published on: July 22, 2015
Modification of supported lipid membranes by atomic force microscopy
S L Brandow1, D C Turner, B R Ratna
1Center for Biomolecular Science and Engineering, Naval Research Laboratory, Washington, DC 20375-5000 USA.
Biophysical Journal
|May 12, 2009
Abstract:
The atomic force microscope (AFM) was used to structurally modify supported lipid bilayers in a controlled quantitative manner. By increasing the force applied by the AFM tip, lipid was removed from the scanned area, leaving a cut through the lipid bilayer. Cuts were repaired with the AFM by scanning the region with a controlled force and driving lipid back into the cut. A slow self-annealing of cuts was also observed.
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