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Customised birthweight centiles are useful for identifying small-for-gestational-age babies in women with type 2

Janet A Rowan1, Steven Luen, Ruth C Hughes

  • 1Department of Obstetrics, National Women's Hospital, Auckland, New Zealand. jrowan@internet.co.nz

The Australian & New Zealand Journal of Obstetrics & Gynaecology
|May 13, 2009
PubMed

Insights

Customised birthweight centiles identified more babies as small-for-gestational-age (SGA) in women with type 2 diabetes. These customised SGA infants experienced higher rates of preterm birth and stillbirth, indicating significant morbidity.

Area of Science:

  • Perinatal medicine
  • Maternal-fetal medicine
  • Neonatal outcomes

Background:

  • Customised birthweight centiles improve small-for-gestational-age (SGA) identification over population centiles.
  • Validation in obese populations and those with type 2 diabetes is lacking.

Purpose of the Study:

  • Compare SGA rates using population vs. customised centiles in type 2 diabetes pregnancies.
  • Examine perinatal outcomes for customised SGA infants.

Main Methods:

  • Retrospective cohort study of 212 women with type 2 diabetes.
  • Calculated customised and population birthweight centiles.
  • Compared outcomes between SGA (<10th customised centile) and appropriate-for-gestational-age (AGA) infants.

Main Results:

  • Customised centiles identified more SGA infants (15%) than population centiles (7%).
  • Customised SGA infants had higher rates of preterm birth (59% vs 16%) and stillbirth (13% vs 0%).
  • Neonatal unit admission was more common in customised SGA infants (68% vs 34%).

Conclusions:

  • Customised birthweight centiles identify a greater proportion of SGA infants in type 2 diabetes pregnancies.
  • Customised SGA infants exhibit significantly higher rates of perinatal morbidity and mortality.
Abstract

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