Semiparametric regression in size-biased sampling
Related Experiment Video
Updated: Jan 31, 2026

Assessment of Mouse Judgment Bias through an Olfactory Digging Task
Published on: March 4, 2022
1Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA. yqchen@scharp.org
Abstract:
Size-biased sampling arises when a positive-valued outcome variable is sampled with selection probability proportional to its size. In this article, we propose a semiparametric linear regression model to analyze size-biased outcomes. In our proposed model, the regression parameters of covariates are of major interest, while the distribution of random errors is unspecified. Under the proposed model, we discover that regression parameters are invariant regardless of size-biased sampling. Following this invariance property, we develop a simple estimation procedure for inferences. Our proposed methods are evaluated in simulation studies and applied to two real data analyses.
Related Concept Videos
Regression Toward the Mean
Sample Size Calculation
The sample size for the given experiment or sampling effort is fundamental to any study design. Sample size decides the number of...
Confirmation Biases
One-Way ANOVA: Unequal Sample Sizes
One-Way ANOVA: Equal Sample Sizes
Different sample means can result in different values for the variance estimate: variance between samples. This is because the variance between samples is calculated as the product of the sample size and the variance between the...
Hindsight Biases

