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Related Experiment Video

Updated: Jun 23, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

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Infantile colic, prolonged crying and maternal postnatal depression.

Torstein Vik1, Veit Grote, Joauqín Escribano

  • 1Norwegian University of Science and Technology, Trondheim, Norway.

Acta Paediatrica (Oslo, Norway : 1992)
|May 13, 2009
PubMed
Summary

Infant crying and colic are linked to maternal postnatal depression. Even after crying stops, mothers with colicky infants show higher depression scores months later, highlighting a significant association.

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Area of Science:

  • Perinatal mental health
  • Infant behavior and development
  • Maternal psychology

Background:

  • Postnatal depression affects mothers globally, impacting maternal well-being and infant care.
  • Infant crying, particularly colic, is a common parental stressor.
  • Understanding the link between infant crying and maternal mental health is crucial for timely intervention.

Purpose of the Study:

  • To investigate the association between infant crying, infantile colic, and maternal postnatal depression.
  • To examine the temporal relationship between excessive infant crying and maternal depressive symptoms.

Main Methods:

  • Prospective European multicentre study involving 1015 mothers and their infants.
  • Infantile colic and prolonged crying defined by maternal report at 2 and 6 months postpartum.
  • Edinburgh Postnatal Depression Scale (EPDS) administered to mothers concurrently.

Main Results:

  • Infant crying showed a significant association with high EPDS scores at 2 and 6 months postpartum (ORs 4.4 and 10.8, respectively).
  • Over one-third of mothers with infants experiencing prolonged crying had high EPDS scores at 6 months postpartum.
  • Longitudinal analysis revealed mothers of colicky infants had higher odds of high EPDS scores at 6 months, even if crying resolved.

Conclusions:

  • Both infantile colic and prolonged infant crying are significantly associated with elevated maternal depression scores.
  • Infantile colic at 2 months postpartum was notably linked to increased maternal depression scores 4 months later.
  • Findings underscore the importance of addressing infant crying issues to support maternal mental health.