Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 23, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Suprasellar spindle cell lipoma.

Krista L Pekarski1, Richard A Prayson

  • 1Cleveland Clinic Foundation, Institute of Pathology, Cleveland, OH 44195, USA.

Annals of Diagnostic Pathology
|May 13, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preventing Microglial Reactivity Protects from Acute and Progressive Neuronal Dysfunction, Motor Impairments and Sedation following Alcohol Abuse.

bioRxiv : the preprint server for biology·2025
Same author

Cisplatin-Induced APE2 Overexpression Disrupts MYH9 Function and Causes Hearing Loss.

Cancer research communications·2025
Same author

Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer's disease.

Immunity·2025
Same author

Rapid postradiation malignant transformation of a pilocytic astrocytoma in an adult with neurofibromatosis type 1: illustrative case.

Journal of neurosurgery. Case lessons·2024
Same author

Long non-coding RNA lung cancer-associated transcript-1 promotes glioblastoma progression by enhancing Hypoxia-inducible factor 1 alpha activity.

Neuro-oncology·2024
Same author

Clinical presentation and extent of resection impacts progression-free survival in spinal ependymomas.

Journal of neuro-oncology·2024

This report details the first known case of a suprasellar spindle cell lipoma in a pediatric patient. The rare tumor presented with headaches and visual disturbances, requiring surgical evaluation.

Area of Science:

  • Neuropathology
  • Pediatric Neurosurgery
  • Oncology

Background:

  • Spindle cell lipomas are rare benign tumors typically found in the neck or upper back.
  • Suprasellar masses can cause significant neurological deficits due to their proximity to critical structures.

Observation:

  • A 4-year-old male presented with headaches and visual disturbances.
  • Imaging revealed a 4-5 mm suprasellar mass, initially suspected to be a lipoma or dermoid cyst.
  • Pathological examination confirmed a spindle cell lipoma.

Findings:

  • The lesion consisted of mature adipose tissue with intermixed uniform spindle cells and a mucoid matrix.
  • Spindle cells and vasculature showed focal positivity for CD34.
  • No evidence of lipoblasts, mitoses, necrosis, or osseous tissue was found.

More Related Videos

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Related Experiment Videos

Last Updated: Jun 23, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Implications:

  • This case expands the known anatomical locations for spindle cell lipomas.
  • Highlights the importance of considering rare diagnoses in pediatric suprasellar masses.
  • Further research may be needed to understand the behavior and optimal management of this rare tumor in this location.