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Bullosis diabeticorum associated with a prediabetic state
Pablo R Lopez1, Stuart Leicht, Justin R Sigmon
1Division of Dermatology, Department of Internal Medicine, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37604, USA. pablolopezmd@gmail.com
Southern Medical Journal
|May 13, 2009
Summary
Bullosis diabeticorum, or diabetic bullae, are skin blisters strongly indicating diabetes. This case highlights their occurrence in prediabetes, prompting diabetes screening.
Area of Science:
- Dermatology
- Endocrinology
- Internal Medicine
Background:
- Bullosis diabeticorum (diabetic bullae) is a rare, non-inflammatory blistering skin condition.
- It is considered virtually diagnostic of diabetes mellitus.
- These blisters typically appear on the extremities (acral distribution).
Observation:
- Diabetic bullae are usually painless, tense, and superficial.
- They typically heal within 2-6 weeks without scarring.
- Potential complications include secondary bacterial infection or hemorrhage.
Findings:
- The diagnosis in non-diabetic individuals warrants diabetes screening.
- This case presents recurrent bullae in a prediabetic patient.
- The clinical features and significance of bullosis diabeticorum are reviewed.
Implications:
- Bullosis diabeticorum can be an early indicator of diabetes or prediabetes.
- Early identification may facilitate timely intervention and management of glucose intolerance.
- This condition underscores the importance of dermatological signs in metabolic disease diagnosis.
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