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Related Experiment Video

Updated: Jun 23, 2026

Doppler Optical Coherence Tomography of Retinal Circulation

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Cross-correlation-based image acquisition technique for manually-scanned optical coherence tomography.

Adeel Ahmad¹, Steven G Adie, Eric J Chaney

¹Beckman Institute for Advanced Science and Technology, Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

|May 13, 2009

Summary

A new Optical Coherence Tomography (OCT) technique allows manual scanning by correcting for speed variations. This enables clear OCT imaging during procedures like biopsies and catheterizations.

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Area of Science:

Biomedical Optics
Medical Imaging Technology

Background:

Optical Coherence Tomography (OCT) is a crucial imaging modality.
Manual scanning in OCT is challenging due to variable scan speeds and motion artifacts.
Existing OCT systems often require precise, automated scanning for optimal image quality.

Purpose of the Study:

To develop and validate a novel image acquisition technique for OCT enabling manual lateral scanning.
To compensate for non-uniform scan velocities and abrupt stops during manual data acquisition.
To demonstrate the feasibility of assembling high-quality OCT images from manually acquired datasets.

Main Methods:

A new image acquisition technique for OCT was developed.
The technique utilizes feedback from the correlation between consecutive A-scans to compensate for lateral scan velocity variations.
The method was tested on phantom samples and biological tissues.

Main Results:

Successful assembly of OCT images from manually scanned datasets was achieved.
The technique effectively compensated for non-uniform scan velocity and motion artifacts.
High-quality OCT images were reconstructed despite challenges in manual data acquisition.

Conclusions:

The novel OCT image acquisition technique enables reliable manual lateral scanning.
This advancement facilitates OCT imaging in challenging clinical scenarios, including needle-guided biopsy and catheter-based procedures.
The technique supports the creation of large field-of-view images using hand-held probes for intraoperative imaging.