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Stimulatory action of calcium L-threonate on ascorbic acid uptake by a human T-lymphoma cell line
1Department of Pharmacology, University of Mississippi School of Pharmacy, University 38677.
Life Sciences
|January 1, 1991
Abstract:
The effects of preincubation of human T-lymphoma cells with increasing concentrations of calcium L-threonate on the uptake of L-[1-14C]ascorbic acid were examined. Calcium L-threonate (0-1,000 mg%) stimulated ascorbic acid (1.25 mg%) uptake in a dose-dependent manner. These results indicate that calcium threonate and possibly other ascorbic acid metabolites have biological activity and potential pharmacological applications.