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[Haemophilus influenzae b among bacterial meningitis in Bamako (2002-2004)]
Abstract:
In Mali little study exist on the meningitis with Haemophilus influenzae b (Hib). This weak data availability on Hib meningitis, didn't permit to introduce the immunization against this pathology in the Expanded Program Immunization (EPI) of Mali. The present survey aims to improve the availability of the data on Hib meningitis and to advocate for the introduction of immunization against Hib in EPI in Mali. The survey consisted to the exploitation of spinal fluid examination data for the suspected cases of meningitis, sent by the different health centers to National Institute for Public Health Research (INRSP) on the period going from October 1st, 2002 to September 30, 2004. According to the survey, on 230 cases of meningitis whose germs have been identified to the latex and the culture, Hib occupies the 3rd place with 21.3% among the bacterial meningitises. In Bamako Hib occupies the 2nd place (27.4%) according to the source. The persons less than 1 year (59.6%) were the more affected (p < 0.001) and the diseases distribution has been observed during the dry seasons (51.0%) and rainy (49.0%) without meaningful impact of temperature and rainfall (p > 0.05) (p = 0.8249). The cases of Hib identified were more sensitive to ciprofloxacine (100%) and to ceftriaxone (100%). Taken into consideration the cost raised of quinolones and cephalosporines, and in reference to the high mortality and frequent complications known of Hib meningitis, the introduction of immunization against Haemophilus influenzae in the Expanded Program Immunization should contribute to a better control of this disease.
Insights
Haemophilus influenzae type b (Hib) meningitis is a significant concern in Mali, affecting infants and requiring effective control strategies. Introducing Hib vaccination into Mali's Expanded Program on Immunization is crucial for disease management.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Context:
- Limited data on Haemophilus influenzae type b (Hib) meningitis in Mali hinders public health interventions.
- Hib meningitis poses a significant threat, particularly to infants under one year old.
Purpose:
- To assess the prevalence of Hib meningitis in Mali.
- To advocate for the inclusion of Hib vaccination in the national Expanded Program on Immunization (EPI).
Summary:
- A survey of meningitis cases from 2002-2004 identified Hib as the third most common bacterial cause (21.3%).
- Infants under one year were most affected (59.6%). Identified Hib strains were sensitive to ciprofloxacin and ceftriaxone.
Impact:
- The findings support the urgent need for Hib vaccination in Mali's EPI to reduce disease burden.
- Implementing Hib immunization can significantly improve control of this severe infection.
Related Concept Videos
Bacterial Meningitis I: Introduction
Bacterial Meningitis
Bacterial Meningitis II: Pathophysiology
Viral Meningitis
Cryptococcal Meningitis
Influenza

