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Updated: Jun 23, 2026
Extraction and Analysis of Taiwanese Green Propolis
Published on: January 7, 2019
Terpenoid constituents of Abies chensiensis with potential anti-inflammatory activity
Yong-Li Li1, Xian-Wen Yang, Su-Mei Li
1Department of Natural Product Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China.
Abstract:
Six new triterpenes (neoabieslactones A-F, 1-6) and 17 known compounds were isolated from the aerial parts of Abies chensiensis. The structures of the new triterpenes were proposed by 1D and 2D NMR spectroscopy. Compound 1 was confirmed structurally by X-ray crystallography. In a bioassay against LPS-induced NO production in RAW264.7 macrophages, three compounds, neoabieslactone E (5), (12R,13R)-8,12-epoxy-14-labden-13-ol (7), and manool (8), exhibited IC(50) values of 9.1, 1.9, and 9.6 microg/mL, respectively.
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