Related Experiment Video
Updated: Jun 23, 2026

Microinjection for Transgenesis and Genome Editing in Threespine Sticklebacks
Published on: May 13, 2016
The genomic 'inner fish' and a regulatory enigma in the vertebrates
1Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892, USA. malonej@niddk.nih.gov
Abstract:
Information on how genomic information from fish to human encodes the same tissues has until now emerged one gene at a time. The study published in this issue now provides lists of genes and their expression levels for 20 vertebrate tissues spanning 450 million years of vertebrate evolution. It reveals a core set of genes with similar tissue-expression patterns yet no common regulatory signatures--a gene-expression paradox.
Related Concept Videos
Cis-regulatory Sequences
Cis-regulatory Sequences
Osmoregulation in Fishes
Organization of Genes
Lampbrush Chromosomes
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops resemble the...
Position-effect Variegation

