Treatment and chemoprevention of NSAID-associated gastrointestinal complications

Edward J Frech1, Mae F Go

  • 1GI Section, George E Wahlen Department of Veterans Affairs Medical Center;

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Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
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Drugs for Treatment of Ulcerative Colitis in IBD

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In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
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