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Updated: Aug 27, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
The magnetic field dependence of proton spin relaxation in tissues
R G Bryant1, D A Mendelson, C C Lester
1Department of Biophysics, University of Rochester Medical Center, New York 14642.
Abstract:
The magnetic field dependence of water-proton relaxation is reported for a simple protein solution, a cross-linked protein solution, and a series of rat tissues, fresh, dried and rehydrated. The shape of the magnetic field dependence associated with water proton relaxation in tissues is accounted for by magnetic dipole-dipole interactions between the mobile water spins and the immobile spin populations of the nonrotating components of the tissue coupling the behavior of the immobilized spin system to that of the mobile water spin system. The effect of this coupling is to impart the field dependence of the relaxation associated with the immobilized spin population to that of the mobile water spins that are observed in most relaxation and imaging experiments.
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