Papillary fibroelastoma of the aortic valve as a cause of transient ischemic attack
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Updated: Jun 23, 2026

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Published on: March 31, 2023
Mehmet H Akay1, Moritz Seiffert, David A Ott
1Department of Cardiovascular Surgery, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas 77030, USA. mhakay@hotmail.com
Insights
Cardiac tumors can cause embolic neurologic events. This case highlights a papillary fibroelastoma of the aortic valve as a source of transient ischemic attack.
Area of Science:
- Cardiology
- Neurology
- Oncology
Background:
- Embolic neurologic events necessitate a thorough cardiac evaluation to identify potential underlying causes.
- Cardiac tumors are an uncommon but critical differential diagnosis in patients presenting with embolic phenomena.
Observation:
- A 42-year-old woman experienced a transient ischemic attack (TIA).
- Diagnostic workup revealed the embolic source to be a papillary fibroelastoma.
- The tumor was identified as originating from the aortic valve.
Findings:
- Papillary fibroelastoma of the aortic valve can manifest as a neurologic event.
- This specific cardiac tumor can embolize, leading to cerebrovascular events such as TIA.
Implications:
- Clinicians should consider cardiac tumors, particularly papillary fibroelastomas, in the differential diagnosis of embolic neurologic events.
- Early identification and management of cardiac tumors are crucial to prevent recurrent embolic events and improve patient outcomes.
- This case underscores the importance of comprehensive cardiac imaging in the evaluation of unexplained embolic strokes.
Abstract:
Diagnostic evaluation of embolic neurologic events requires the consideration of cardiac causes. We recently encountered a case that emphasizes the importance of cardiac tumor as a source of embolic events. We present herein the case of a 42-year-old woman who suffered a transient ischemic attack caused by a papillary fibroelastoma that originated from the aortic valve.
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