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Caloric intake and weight gain in a neonatal intensive care unit
Patrícia Janeiro1, Manuel Cunha, António Marques
1Neonatal Intensive Care Unit (NICU), Department of Paediatrics, Hospital Fernando Fonseca, IC 19. 2720-276 Amadora, Portugal. patricia.janeiro@gmail.com
Insights
Early and increased protein and lipid intake in very-low-birthweight (VLBW) infants did not significantly improve weight z scores at discharge. While nutritional deficits were lower, growth outcomes remained similar between groups.
Area of Science:
- Neonatology
- Pediatric Nutrition
- Infant Growth
Background:
- Very-low-birthweight (VLBW) infants often experience suboptimal growth.
- Optimizing early nutrition is crucial for improving outcomes in VLBW infants.
Purpose of the Study:
- To investigate the impact of earlier and higher protein and lipid intake on weight gain in VLBW infants.
- To compare nutritional intake and growth parameters between two groups of VLBW infants with different feeding protocols.
Main Methods:
- Retrospective study comparing two groups of VLBW infants (n=28 in group 1, n=18 in group 2).
- Group 1 received lower protein/lipid intake starting later (postnatal day 2/3).
- Group 2 received higher protein/lipid intake starting earlier (postnatal day 1).
Main Results:
- Group 2 had significantly higher caloric intake (p < 0.05).
- Group 1 exhibited a higher cumulative nutritional deficit (p <= 0.01).
- Weight z scores at discharge were significantly lower than at birth for both groups (p <= 0.01), with no significant difference between groups.
Conclusions:
- Earlier and higher protein and lipid administration in VLBW infants did not lead to improved weight z scores at discharge.
- Despite reduced nutritional deficits, the applied feeding strategies did not significantly enhance growth outcomes in this cohort.
Abstract:
The aim of this paper was to study the weight gain in very-low-birthweight (VLBW) infants by adopting earlier and higher intake of proteins and earlier intake of lipids. We studied 28 VLBW infants admitted to Neonatal Intensive Care Unit during the year 2004 (group 1) and 18 during the first semester of 2006 (group 2). Dietary intakes for group 1 were: 1 g kg(-1) day(-1) of proteins started at postnatal day 2 (P2) and 0.5-1 g kg(-1) day(-1) of lipids at P3; for group 2, 1-1.5 g kg(-1) day(-1) of proteins and 0.5-1 g kg(-1) day(-1) of lipids, both started at P1. Caloric intake was significantly higher in group 2 (p < 0.05), whereas cumulative nutritional deficit was higher in group 1 (p < or = 0.01). Weight z scores were significantly lower at discharge comparing with z scores at birth for each group (p < or = 0.01), with no differences between the two groups. Despite a higher protein intake which resulted in a lower nutritional deficit, the weight z score did not improve significantly at discharge.
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