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Published on: June 26, 2020
Hepatitis G virus infection in multitransfused Egyptian children
Khaled Mohamed Salama1, Osima El-Sayed Selim
1Department of Pediatrics, Cairo University, Cairo, Egypt. ksalama2@yahoo.com
Abstract:
The purpose of this study was to identify the magnitude of the hepatitis G virus infection in 33 multitransfused cases and 20 matched controls. All were tested for liver biochemical profile, HBsAg, HCV-antibody, HGV-RNA, and antibody to envelop protein E(2). HGV was detected alone in 61% of the multitransfused cases and 15% of the controls. Hepatitis markers were negative in 21% of cases versus 70% of controls. HGV envelope antibody was detected in 12% of cases, and none of controls. Mean values of transaminases in HGV positives and negatives showed no significant differences. HGV infection is highly prevalent in Egyptian children with no impact in infected cases.
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