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Published on: October 24, 2025
Sperm cryopreservation practices among adolescent cancer patients at risk for infertility
James L Klosky1, Mary E Randolph, Fariba Navid
1Department of Behavioral Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA. james.klosky@stjude.org
Abstract:
To assess sperm cryopreservation among males newly diagnosed with cancer aged 13 years and older, attending oncologists assigned infertility risk (yes/no) to patients and reported whether their patients engaged in sperm cryopreservation. Only 28.1% of informed at-risk patients banked sperm. Utilization of sperm banking was significantly associated with a diagnosis of central nervous system (CNS) malignancy or non-CNS solid tumor diagnosis, higher socioeconomic status, and not being a member of an Evangelical religious group. These results suggest that sperm banking is underutilized among adolescent males newly diagnosed with cancer, and that strategies to increase the engagement in this fertility preservation method are needed.
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