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Micelles

Micelles

Micelle formation is an intricate process that hinges on the properties of amphiphilic or amphipathic molecules and the conditions of the system in which they are found. Amphiphilic molecules, which have both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts, play a critical role in this process.In aqueous environments, these molecules arrange themselves such that their hydrophilic heads are turned towards the water phase, while their hydrophobic tails are oriented away...

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Microfluidic Fabrication of Core-Shell Microcapsules carrying Human Pluripotent Stem Cell Spheroids

Microfluidic Fabrication of Core-Shell Microcapsules carrying Human Pluripotent Stem Cell Spheroids

Published on: October 13, 2021

Emulsion-templated liquid core-polymer shell microcapsule formation.

Zhuo Ao¹, Zhi Yang, Jianfang Wang

¹Department of Chemistry and Physics, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.

Langmuir : the ACS Journal of Surfaces and Colloids

|May 14, 2009

Summary

This summary is machine-generated.

We developed a simple method for creating stable, hollow polymer microcapsules using Pickering emulsions and biodegradable poly(lactic-co-glycolic acid) (PLGA). These microcapsules are ideal for encapsulating hydrophobic functional molecules.

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Preparation of Hollow Polystyrene Particles and Microcapsules by Radical Polymerization of Janus Droplets Consisting of Hydrocarbon and Fluorocarbon Oils

Preparation of Hollow Polystyrene Particles and Microcapsules by Radical Polymerization of Janus Droplets Consisting of Hydrocarbon and Fluorocarbon Oils

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Preparation of Hollow Polystyrene Particles and Microcapsules by Radical Polymerization of Janus Droplets Consisting of Hydrocarbon and Fluorocarbon Oils

Preparation of Hollow Polystyrene Particles and Microcapsules by Radical Polymerization of Janus Droplets Consisting of Hydrocarbon and Fluorocarbon Oils

Published on: January 25, 2018

Area of Science:

Materials Science
Chemical Engineering
Nanotechnology

Background:

Encapsulating functional molecules in hollow microspheres is crucial for applications like drug delivery.
Existing methods often lack scalability for industrial production.

Purpose of the Study:

To develop a straightforward and scalable method for fabricating stable microcapsules.
To create microcapsules suitable for encapsulating hydrophobic molecules.

Main Methods:

Templating an oil-in-water emulsion using polystyrene latex particles (Pickering emulsion).
Stabilizing the emulsion interface with a monolayer of polystyrene particles.
Forming a robust polymer shell using biodegradable poly(lactic-co-glycolic acid) (PLGA) precipitation.

Main Results:

Successfully fabricated liquid core-polymer shell microcapsules.
The microcapsules demonstrated stability, retaining integrity after air drying.
The method utilizes readily available materials and a simple process.

Conclusions:

The developed method offers a promising approach for industrial-scale production of microcapsules.
The stable microcapsules are well-suited for encapsulating hydrophobic functional molecules.
This technique has significant potential for various applications, including drug delivery and material science.