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Updated: Jun 23, 2026

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Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals
Published on: February 14, 2019
Rewritable glycochips
L G Harris1, W C E Schofield, K J Doores
1Department of Chemistry, Science Laboratories, Durham University, Durham DH1 3LE, UK.
Journal of the American Chemical Society
|May 15, 2009
Abstract:
We describe microarraying of carbohydrates for protein screening using either disulfide bridge or Schiff base imine immobilization chemistries on plasmachemical deposited functional nanolayers. The commonly observed issue of nonspecific background binding of proteins is overcome by spotting carbohydrates through a protein-resistant overlayer yielding spatially localized interaction with a reactive functional underlayer.

