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When speed truly matters, openness is the answer.

Antonio Marturano¹

¹Sacred Heart Catholic University of Rome and LUISS University of Rome, Italy. marturanoa@luiss.it

|May 15, 2009

Summary

This study compares proprietary patent-and-publish genomics research with free and open-source methodologies. Open-source science prioritizes intrinsic values, fostering a more transformative approach to research compared to transactional patenting.

Area of Science:

Genomics Research Ethics
Biotechnology Methodologies
Intellectual Property in Science

Background:

Genomic research has accelerated due to advancements in computer technology.
Two primary methodologies, patent-and-publish and open-source, compete in the field.
The open-source approach emerged as an alternative to proprietary models.

Purpose of the Study:

To analyze the ethical implications of competing genomic research methodologies.
To offer a novel perspective beyond mainstream legal and public policy analyses.
To compare the proprietary regime (J. Craig Venter) with open-source methodologies (John Sulston).

Main Methods:

Comparative analysis of two distinct genomic research methodologies.
Examination of the 'patent-and-publish' (proprietary) regime.

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Description of 'free and open-source' (FLOSS) methodologies in biotechnology.

Main Results:

The patent-and-publish method is transactional, exchanging patents for research funds.
Free and open-source methodology (FLOSS) is transformational, driven by scientific ideals.
FLOSS prioritizes intrinsic scientific goods over extrinsic rewards.

Conclusions:

Open-source methodologies represent a visionary ideal in science.
This approach fosters a prioritization of intrinsic values in research.
Ethical considerations favor transformational, open-source models in genomics.