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Testicular autoregulation: possible role for 7-alpha-hydroxylated androgens
1Medical Service, US Department of Veterans Affairs, East Orange, New Jersey 07019.
Medical Hypotheses
|July 1, 1991
Abstract:
Pituitary FSH secretion appears to be supported by a factor distinct from the gonadotropin-releasing hormone (Gn-RH). The ratio of FSH to LH is positively correlated with testicular steroid 5 alpha-reductase activity and negatively correlated with testicular steroid 7 alpha-hydroxylase under various experimental conditions. Literature describing interactions among the above and other factors is reviewed here.