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Published on: June 2, 2014
Cough headache: a study of 83 consecutive patients
Cephalalgia : an International Journal of Headache
|May 15, 2009
Summary
Primary cough headache shows high remission rates and responds well to indomethacin. However, clinical features cannot reliably distinguish primary from secondary cough headache, necessitating neuroimaging for all patients.
Area of Science:
- Neurology
- Headache Medicine
Background:
- Cough headache is a primary headache disorder triggered by coughing.
- Differentiating primary from secondary cough headache is crucial for appropriate management.
- Previous studies suggest neuroimaging is necessary, but clinical differentiation remains challenging.
Purpose of the Study:
- To compare clinical characteristics and outcomes of primary versus secondary cough headache.
- To identify predictors of treatment response and long-term prognosis.
- To evaluate the diagnostic utility of clinical features versus neuroimaging.
Main Methods:
- A cohort of 83 patients with cough headache was retrospectively analyzed.
- Patients underwent clinical evaluation and brain imaging.
- Treatment response to indomethacin and long-term remission rates were assessed.
Main Results:
- 89.2% of patients were diagnosed with primary cough headache; 10.8% had secondary causes, often posterior fossa lesions.
- Primary cough headache showed a significantly higher response rate to indomethacin (72.7%) compared to secondary (37.5%).
- 83.9% of primary cough headache patients achieved complete remission; however, some exceeded the diagnostic duration criteria.
Conclusions:
- Clinical features alone are insufficient to differentiate primary from secondary cough headache.
- Neuroimaging is essential for all patients diagnosed with cough headache.
- Primary cough headache generally has a favorable prognosis with indomethacin treatment.
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