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Updated: Jun 23, 2026
Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
Maxillary sinus augmentation in humans using cortical porcine bone: a histological and histomorphometrical evaluation
Antonio Scarano1, Adriano Piattelli, Vittoria Perrotti
1Dental School, University of Chieti-Pescara, Via F. Sciucchi 63, Chieti, Italy.
Background:
Bone substitutes, such as allografts, xenografts, and alloplasts, have been proposed in several augmentation procedures.
Purpose:
The aim of the present study was a histologic and histomorphometric evaluation of specimens retrieved 4 or 6 months after sinus augmentation using cortical porcine bone augmentation material.
Materials And Methods:
A total of 77 specimens, retrieved after 4 and 6 months from augmented sinuses, were used in this study. The specimens were processed to be observed under light microscopy. Histomorphometric measurements were presented as means ± standard deviations.
Results:
Most of the particles were surrounded by newly formed bone with large osteocyte lacunae. Histomorphometry showed that, after 4 months, the newly formed bone represented 28%, marrow spaces 36%, the residual graft material 37%, while, after 6 months, the newly formed bone represented 31%, marrow spaces 34%, while the residual graft material was 37%.
Conclusion:
The present results show that cortical porcine bone is a biocompatible, osteoconductive biomaterial that can be used for maxillary sinus augmentation procedures without interfering with the normal reparative bone processes.
