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Updated: Jun 23, 2026

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
Published on: December 22, 2015
Bone structure changes in iliac crest grafts combined with implants.
Jan Willem Verhoeven1, Jan M Ruijter, Ronald Koole
1Department of Oral & Maxillofacial Surgery, Prosthodontics and Special Dental Care, University Medical Center, Utrecht, The Netherlands. j.w.verhoeven@umcutrecht.nl
Onlay bone grafting combined with dental implants shows bone remodeling in the mandible. Early changes involve resorption and formation, indicating graft integration and architectural adaptation over the first year.
Area of Science:
- Oral and Maxillofacial Surgery
- Biomaterials Science
- Radiology
Background:
- Mandibular onlay grafts with implants undergo predictable radiographic density changes.
- Understanding graft remodeling and trabecular structure is crucial for long-term success.
Purpose of the Study:
- To evaluate bone structure changes following mandibular onlay grafting with simultaneous implant placement.
- To correlate radiographic density changes with alterations in trabecular bone architecture.
Main Methods:
- Utilized standardized extraoral radiographs of 16 mandibular sides.
- Employed the Carl Zeiss Vision KS 400 3.0 imaging system for bone structure analysis.
- Measured parameters including trabecular and cavity dimensions, endpoints, branching points, skeleton length, branch angle/direction, and texture.
Main Results:
- No significant differences in bone structure were observed relative to implant position.
- Early cortical changes indicated partial resorption and increased structural complexity.
- The graft's upper spongiosa showed bone formation throughout the first postoperative year, while the upper cortex exhibited progressive resorption in the later stages.
Conclusions:
- The employed radiographic technique effectively monitors bone graft architectural changes.
- Observed architectural modifications in the graft align with documented changes in bone density.
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