Related Experiment Video
Updated: Jun 23, 2026

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety
Published on: November 11, 2022
Social anxiety disorder in the West and in the East
1Department of Psychiatry, University of Cape Town, Groote Schuur Hospital (J-2), Anzio Rd., Observatory 7925, Cape Town, South Africa. dan.stein@uct.ac.za
Background:
Although social anxiety disorder (SAD) is one of the most prevalent psychiatric disorders in epidemiological surveys, concepts of social anxiety have varied from time to time and place to place. In recent years, however, similar assessments and treatments have been utilized across the world.
Methods:
In this paper, current concepts of SAD in the West and the partially related condition known as taijin kyofusho (TKS) in the East are summarized, and trials of selective serotonin reuptake inhibitors (SSRIs) that have been undertaken in both the United States/Europe and in Japan for social anxiety symptoms are reviewed.
Results:
Despite differences in the conceptualization of SAD and TKS, social anxiety is a prevalent symptom in many parts of the world. Fluvoxamine is more effective than placebo in randomized controlled trials of SAD in the West and the East.
Conclusions:
Patients suffering from SAD in different parts of the world share many features in common, and certain SSRIs are an effective treatment for this condition globally.
Related Concept Videos
Social Anxiety Disorder
Self-Esteem and Culture
Generalized Anxiety Disorder
Anxiety: Overview
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Personality Disorders: Paranoid and Schizoid
Paranoid Personality Disorder
Paranoid personality disorder is...
Need for Self-Esteem
