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Routes of Persuasion02:20

Routes of Persuasion

Persuasion is the process of changing our attitude toward something based on some kind of communication. Much of the persuasion we experience comes from outside forces. How do people convince others to change their attitudes, beliefs, and behaviors? What communications do you receive that attempt to persuade you to change your attitudes, beliefs, and behaviors?
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Social Traps

Social traps are negative situations where people get caught in a direction or relationship that later proves to be unpleasant, with no easy way to back out of or avoid. The concept was orignally introduced by John Platt who applied psychology to Garrett Hardin's "Tragedy of the Commons", where in New England herd owners could let their cattle graze in the common ground. This situation seems like a good idea, but an individual could have an advantage. If they owned more cows, the larger...
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Low-stress Route Learning Using the Lashley III Maze in Mice
09:14

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Published on: May 22, 2010

Aging: shall we take the high road?

Ikue Mori1, Hiroyuki Sasakura

  • 1Laboratory of Molecular Neurobiology, Department of Molecular Biology, Graduate School of Science, Nagoya University and CREST-JST, Nagoya, Japan. m46920a@nucc.cc.nagoya-u.ac.jp

Current Biology : CB
|May 15, 2009
PubMed
Summary
This summary is machine-generated.

Low temperatures extend lifespan in ectotherms, while high temperatures shorten it. A study in Caenorhabditis elegans reveals how thermosensory neurons use steroid signaling to protect lifespan against heat.

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Area of Science:

  • Gerontology
  • Neurobiology
  • Molecular Biology

Background:

  • Ectotherms exhibit temperature-dependent lifespan, with lower temperatures increasing longevity and higher temperatures decreasing it.
  • Understanding the molecular mechanisms underlying lifespan regulation in response to environmental temperature is crucial.

Discussion:

  • Thermosensory neurons in Caenorhabditis elegans play a critical role in modulating lifespan under thermal stress.
  • These neurons counteract the detrimental effects of high temperatures on lifespan through neural regulation of a steroid signaling pathway.

Key Insights:

  • Specific thermosensory neurons can actively protect lifespan from the negative impacts of elevated temperatures.
  • The study identifies a novel mechanism where neural activity influences systemic aging pathways via steroid hormone signaling.

Outlook:

  • This research opens new avenues for understanding neuro-endocrine control of aging.
  • Further investigation into this pathway could reveal therapeutic targets for age-related diseases.