Related Experiment Video
Updated: Jun 23, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
Published on: June 20, 2014
Construction of nitrogen-containing heterocycles by C-H bond functionalization
Praew Thansandote1, Mark Lautens
1Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON M5S3H6, Canada.
Abstract:
Nitrogen heterocycles are abundant in natural products and pharmaceuticals. An emerging interest among synthetic chemists is to use C-H functionalization to construct the nitrogen-containing core of these heterocycles. The following article will provide a brief overview of this concept with respect to the type of C-H bond functionalized.
More Related Videos
07:50Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
Published on: May 26, 2019
10:17Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
Related Concept Videos
Five-Membered Heterocyclic Aromatic Compounds: Overview
Electrophilic Aromatic Substitution: Nitration of Benzene
Preparation of Nitriles
Aldehydes and Ketones with HCN: Cyanohydrin Formation Overview
Diazonium Group Substitution: –OH and –H
Cycloaddition Reactions: Overview