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[Bone marrow transplantation for pediatric solid tumor]
S Yokoyama1, H Hirakawa, T Tajima
1Department of Surgery, Tokai University, School of Medicine, Isehara, Japan.
Nihon Geka Gakkai Zasshi
|September 1, 1991
Abstract:
Bone marrow transplantation permits the use of greatly intensified cytoreductive therapy for cancer. Since 1981, fifteen children with disseminated solid tumor were treated by this method (6 Nb1, 6 Lymphoma, 1 PNET, 1 Hb1, 1 YST.). Eight out of 15 (53%) have been alive and well 2-96 (median 45) months after BMT. Though toxicity is severe, high dose chemo-radiotherapy using BMT after reaching complete remission with well scheduled induction chemotherapy and surgery is concluded as a treatment of choice for pediatric malignant solid tumor in advanced stage.