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Updated: Jun 23, 2026

Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology
Published on: August 18, 2014
Preclinical compounds for the treatment of overactive bladder
Konstantinos Giannitsas1, Angelis Konstantinopoulos, Christos Patsialas
1Urology Department, Urology Patras University General Hospital, Rion, Patras, Greece.
Background:
Overactive bladder is a prevalent and bothersome condition. Existing pharmacotherapy with antimuscarinics improves symptoms and quality of life but there are certain limitations in efficacy and tolerability.
Objective:
To review novel, recently patented compounds for the treatment of overactive bladder.
Methods:
The European Patent Office database was searched for compounds that emerged in the last 3 years.
Results/Conclusion:
Overactive bladder pathophysiology and treatment is an active field of research. Molecules that modulate/inhibit afferent nerve pathways are the focus of interest and the most promising field of overactive bladder drug development.
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