Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Surgical infection and its backgrounds].

S Hikida1, H Mizote, Y Tanaka

  • 1First Department of Surgery, Kurume University School of Medicine, Japan.

Nihon Geka Gakkai Zasshi
|September 1, 1991
PubMed
Summary

Preoperative nutritional support aids immune recovery in esophageal cancer surgery patients. Postoperative infections highlight the need for optimized antibiotic use and hospital infection control to prevent resistant bacteria.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study.

Cancer·1992
Same author

[Radiolocalization of human esophageal cancer in athymic mice by a monoclonal antibody KIS-1: preliminary report].

Nihon Geka Gakkai zasshi·1992
Same author

Cystic adult granulosa cell tumor causing precocious pseudopuberty in a six-year-old girl.

Acta paediatrica (Oslo, Norway : 1992)·1992
Same author

[Adult T-cell leukemia with various pulmonary complications].

Nihon Kyobu Shikkan Gakkai zasshi·1992
Same author

Immuno-electron-microscopic localization of basic fibroblast growth factor in the dystrophic mdx mouse masseter muscle.

Cell and tissue research·1992
Same author

[Two cases of hypothyroidism with echocardiographic features similar to cardiomyopathy: one simulates hypertrophic and the other dilated cardiomyopathy].

Kokyu to junkan. Respiration & circulation·1992

Area of Science:

  • Surgical oncology
  • Infectious disease
  • Nutritional immunology

Context:

  • Esophageal cancer surgery poses significant risks of surgical site infections.
  • Understanding host and pathogen factors is crucial for managing postoperative complications.
  • Evaluating antibiotic administration strategies and bacterial translocation is essential.

Purpose:

  • To investigate host factors (nutrition, immune response) and pathogen factors (surgical site contamination, bacterial translocation) influencing surgical infections in esophageal cancer patients.
  • To compare the efficacy of different antibiotic administration methods.
  • To identify the relationship between oral/esophageal flora and postoperative respiratory infections.

Summary:

  • Preoperative nutritional support improved immune function recovery. Postoperative infections were associated with delayed immunological recovery and specific nutritional needs (BCAA, glutamine, essential fatty acids).

Related Experiment Videos

  • Surgical wounds in the neck, chest, and abdominal walls were common sites of contamination. Continuous antibiotic infusion (1g/hr x 4) was excessive.
  • No correlation was found between intraoperative oral/esophageal bacteria and postoperative airway bacteria. Antibiotic-resistant bacteria (Pseudomonas, MRSA) were detected in airways.

    • Impact:

    • Nutritional support is vital for bolstering the host defense system.
    • Antibiotic administration should be tailored to the operative process.
    • Preventing hospital-acquired infections is critical for managing postoperative respiratory infections.