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SELDI protein chip technology for the detection of serum biomarkers for liver disease
Lei Chen1, Sarwat Fatima, Jirun Peng
1Department of Hepatobiliary Surgery, Peking University People's Hospital, 11 Xizhimen South Street,Beijing, China. chentiger@medmail.com.cn
Protein and Peptide Letters
|May 16, 2009
Abstract:
The need to identify disease biomarkers is critical to ensure fast diagnosis and timely treatment. Surface enhanced laser desorption/ionization time-of-fight mass spectrometry (SELDI-TOF-MS) is a widely used technology platform for diagnostic biomarker discovery. This short review provides an overview of how it functions and also describes its advantages and drawbacks.
