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The search for a human Holliday junction resolvase

Stephen C West1

  • 1London Research Institute, Clare Hall Laboratories, Cancer Research UK, South Mimms, Hertfordshire, UK. stephen.west@cancer.org.uk

Biochemical Society Transactions
|May 16, 2009
PubMed
Summary

Holliday junctions are crucial for chromosome segregation. Human GEN1 protein, identified in 2008, resolves these DNA structures, similar to bacterial resolvases.

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