Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Developing a Bone-Mimicking Microenvironment: Surface Coating Method for Investigating Bone Remodeling <i>in Vitro</i>.

ACS biomaterials science & engineering·2025

Same author

Differential proteomics profile of microcapillary networks in response to sound pattern-driven local cell density enhancement.

Biomaterials and biosystems·2024

Same author

Osteochondral explants for diarthrodial joint diseases: bridging the gap between bench and bedside.

European cells & materials·2022

Same author

The production and application of bacterial exopolysaccharides as biomaterials for bone regeneration.

Carbohydrate polymers·2022

Same author

Evaluation of the influence of platelet-rich plasma (PRP), platelet lysate (PL) and mechanical loading on chondrogenesis in vitro.

Scientific reports·2021

Same author

Sodium hyaluronate supplemented culture medium combined with joint-simulating mechanical loading improves chondrogenic differentiation of human mesenchymal stem cells.

European cells & materials·2021

Search research articles

Related Experiment Video

Updated: Jun 23, 2026

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

Nanohydroxyapatite/poly(ester urethane) scaffold for bone tissue engineering.

C I R Boissard¹, P-E Bourban, A E Tami

¹Laboratoire de Technologie des Composites et Polymères, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.

Acta Biomaterialia

|May 16, 2009

Summary

This study developed hydroxyapatite nanoparticles (nHA)/poly(ester urethane) composite scaffolds for tissue engineering. The optimized scaffolds enhance mechanical properties and show potential for bone regeneration.

More Related Videos

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs

Published on: August 8, 2022

Related Experiment Videos

Last Updated: Jun 23, 2026

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs

Published on: August 8, 2022

Area of Science:

Biomaterials Science
Tissue Engineering
Nanotechnology

Background:

Biodegradable viscoelastic poly(ester urethane) scaffolds are promising for tissue engineering.
Hydroxyapatite nanoparticles (nHA) can enhance scaffold properties.

Purpose of the Study:

To prepare and optimize nHA/poly(ester urethane) composite scaffolds using a salt-leaching-phase inverse process.
To investigate the effect of nHA content and process parameters on scaffold properties.

Main Methods:

Salt-leaching-phase inverse process for scaffold fabrication.
Microcomputed X-ray tomography for analyzing nHA dispersion.
Scanning electron microscopy for surface analysis.

Main Results:

Increasing nHA content decreased porosity and pore size, while increasing wall thickness.
Young's modulus improved by 50% with 10 wt.% nHA addition, preserving viscoelasticity.
nHA particles were successfully incorporated into the matrix and on pore surfaces.

Conclusions:

Optimized nHA/poly(ester urethane) composite scaffolds exhibit enhanced mechanical properties.
These scaffolds hold significant potential as osteoconductive materials for bone tissue engineering.