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Published on: April 7, 2020
Chronotype and body composition in bipolar disorder
Isabella Soreca1, Andrea Fagiolini, Ellen Frank
1Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA. sorecai@upmc.edu
Abstract:
We explored whether obesity in patients with bipolar disorder is associated with their chronotype. A group of 29 patients with bipolar I disorder, not currently experiencing an affective episode, were assessed for total body fat, mood symptoms, and self-reported circadian chronotype and sleep quality. Chronotype explained 19% of the variance in body fat, after age, sex, mood state, and sleep quality were accounted for. This association suggested that evening chronotype patients have a higher percentage of total body fat. Evening chronotype could be a proxy for as yet unknown specific causes of the high rate of obesity and obesity-related diseases in bipolar disorder.
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