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Published on: May 8, 2018
Stereotactic body radiation therapy for oligometastases
Simon S Lo1, Achilles J Fakiris, Bin S Teh
1Department of Radiation Medicine, Arthur G James Cancer Hospital, Ohio State University Medical Center, 300 West 10th Avenue, Ste 088A, Columbus, OH 43210, USA. simon.lo@osumc.edu
Expert Review of Anticancer Therapy
|May 19, 2009
Summary
Stereotactic body radiation therapy (SBRT) offers a novel local ablative approach for patients with limited extracranial metastases. Combining SBRT with systemic therapy shows promise for improving outcomes in oligometastatic cancer.
Area of Science:
- Oncology
- Radiation Oncology
- Medical Physics
Background:
- Systemic therapy is standard for metastatic cancer.
- Oligometastases represent an intermediate state between localized and widespread disease.
- Local ablative therapies may benefit select patients with limited metastatic burden.
Purpose of the Study:
- To provide an overview of stereotactic body radiation therapy (SBRT) for extracranial oligometastases.
- To highlight the emerging role of SBRT in managing limited metastatic disease.
- To discuss the potential benefits of SBRT in combination with systemic therapy.
Main Methods:
- Literature review of SBRT applications in extracranial oligometastases.
- Summary of existing clinical experience and outcomes.
- Discussion of SBRT techniques and target sites.
Main Results:
- SBRT is a viable option for local ablation of oligometastases.
- Promising results have been reported for SBRT in the lung, liver, and spine.
- SBRT in combination with systemic therapy may enhance treatment efficacy.
Conclusions:
- SBRT is an effective treatment modality for extracranial oligometastases.
- The integration of SBRT into cancer treatment protocols warrants further investigation.
- SBRT offers a promising therapeutic strategy for select cancer patients.
