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Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...

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Related Experiment Video

Updated: Jun 23, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

Lung cancer.

Alan Neville1

  • 1McMaster University, Hamilton, Ontario, Canada.

BMJ Clinical Evidence
|May 19, 2009
PubMed
Summary

This systematic review evaluates lung cancer treatments, including chemotherapy, radiotherapy, and molecular-targeted therapy for both small cell and non-small cell lung cancer, assessing their effectiveness and safety.

Area of Science:

  • Oncology
  • Pulmonology
  • Evidence-Based Medicine

Background:

  • Lung cancer is a leading cause of cancer mortality, with smoking as the primary risk factor.
  • Small cell lung cancer (SCLC) is typically treated with chemotherapy, while adenocarcinoma, a common non-small cell lung cancer (NSCLC), is often initially treated with surgery.

Purpose of the Study:

  • To systematically review the effects of various treatments for resectable and unresectable non-small cell lung cancer.
  • To evaluate the effectiveness and safety of treatments for small cell lung cancer.

Main Methods:

  • Conducted a systematic review of 86 systematic reviews and randomized controlled trials (RCTs).
  • Searched major databases (Medline, Embase, Cochrane Library) up to May 2008.
  • Included harms alerts from regulatory agencies (FDA, MHRA).

Related Experiment Videos

Last Updated: Jun 23, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

Main Results:

  • A GRADE evaluation was performed to assess the quality of evidence for interventions.
  • Identified numerous interventions for lung cancer treatment.

Conclusions:

  • Presents information on the effectiveness and safety of diverse lung cancer interventions.
  • Covers chemotherapy (various regimens, dose intensification), radiotherapy (CHART, non-CHART), molecular-targeted therapy (gefitinib, erlotinib), palliative care, and prophylactic cranial irradiation.