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Related Concept Videos

Cranial Nerves: Types Part I01:14

Cranial Nerves: Types Part I

Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves, with the first six being essential in sensory perception, motor control, and autonomic functions related to the head and neck.
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
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A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Cranial Nerves: Types Part II01:22

Cranial Nerves: Types Part II

Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
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Cranial Part of Parasympathetic Division

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Related Experiment Video

Updated: Jun 23, 2026

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
09:35

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

Trigeminal neuralgia.

Joanna M Zakrzewska1, Mark E Linskey

  • 1Barts and the London Queen Mary's School of Medicine and Dentistry, London, UK.

BMJ Clinical Evidence
|May 19, 2009
PubMed
Summary
This summary is machine-generated.

This systematic review examines treatments for trigeminal neuralgia, a condition causing severe facial pain. It evaluates the effectiveness and safety of various interventions, including medications and surgical procedures, for managing this neurological disorder.

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Microvascular Decompression: Salient Surgical Principles and Technical Nuances
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Published on: July 5, 2011

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Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
09:35

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Published on: May 10, 2017

Microvascular Decompression: Salient Surgical Principles and Technical Nuances
10:35

Microvascular Decompression: Salient Surgical Principles and Technical Nuances

Published on: July 5, 2011

Area of Science:

  • Neurology
  • Pain Management
  • Evidence-Based Medicine

Background:

  • Trigeminal neuralgia is characterized by sudden, severe, unilateral facial pain in the fifth cranial nerve distribution.
  • Attacks are brief, stabbing, and recurrent, varying in frequency and duration.
  • Remission periods can occur but may shorten over time.

Purpose of the Study:

  • To systematically review and evaluate the effects of various treatments for trigeminal neuralgia.
  • To assess the effectiveness and safety of interventions for this neuropathic pain condition.

Main Methods:

  • A systematic review of medical literature was conducted, searching databases like Medline, Embase, and The Cochrane Library up to September 2007.
  • Included 14 systematic reviews, randomized controlled trials (RCTs), and observational studies.
  • GRADE evaluation was used to assess the quality of evidence for interventions.

Main Results:

  • The review identified and evaluated a range of treatments for trigeminal neuralgia.
  • Evidence quality for different interventions was assessed using the GRADE system.

Conclusions:

  • Information on the effectiveness and safety of numerous interventions is presented.
  • Treatments reviewed include ablative neurosurgical techniques, medications (e.g., carbamazepine, gabapentin), microvascular decompression, and stereotactic radiosurgery.