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Anorexia Nervosa01:28

Anorexia Nervosa

Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Bulimia Nervosa01:30

Bulimia Nervosa

Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
Binge Eating Disorders01:23

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Panic Disorder01:27

Panic Disorder

Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...

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Neurocognitive Profiles and Predictors of Symptom Trajectory During and After Treatment in Adolescent Bulimia Nervosa.

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Related Experiment Video

Updated: Jun 23, 2026

Assessing Activity-based Anorexia in Mice
08:26

Assessing Activity-based Anorexia in Mice

Published on: May 14, 2018

Anorexia nervosa.

James D Lock1, Kathleen Kara Fitzpatrick

  • 1Stanford University, Stanford, CA, USA.

BMJ Clinical Evidence
|May 19, 2009
PubMed
Summary
This summary is machine-generated.

This systematic review examines treatments for anorexia nervosa, finding evidence on various interventions including psychotherapy and medications. It assesses effectiveness and safety to inform clinical practice for this serious eating disorder.

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Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa
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Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa

Published on: October 22, 2015

Area of Science:

  • Eating Disorders
  • Clinical Psychology
  • Pharmacology

Background:

  • Anorexia nervosa is a serious eating disorder characterized by low BMI, fear of weight gain, and health denial.
  • Prevalence is highest in teenage girls, with significant mortality and chronic illness rates.
  • Anorexia nervosa increases the risk of long-term health complications, including bone fractures.

Purpose of the Study:

  • To systematically review the effects of treatments for anorexia nervosa.
  • To evaluate interventions aimed at preventing or treating complications associated with anorexia nervosa.

Main Methods:

  • A systematic review of 40 studies including systematic reviews, RCTs, and observational studies.
  • Searches conducted across major databases (Medline, Embase, Cochrane Library) up to August 2007.
  • Inclusion of harms alerts from regulatory agencies (FDA, MHRA).

Main Results:

  • The review identified evidence on the effectiveness and safety of various interventions.
  • GRADE evaluation was used to assess the quality of evidence for different treatments.
  • Data was synthesized for interventions including psychotherapy, medications, and treatment settings.

Conclusions:

  • Information is presented on the effectiveness and safety of anxiolytic drugs, cyproheptadine, inpatient/outpatient settings, estrogen treatment, psychotherapy, refeeding, SSRIs, and tricyclic antidepressants.
  • The review provides a comprehensive overview of current evidence for anorexia nervosa treatments.
  • Findings aim to guide clinical decisions regarding anorexia nervosa management.