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Updated: Jun 23, 2026
06:15
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
[Proliferative cutaneous epithelioid angiomatous nodule]
Celia Requena Caballero1, M J Nicolau, R Haro
1Servicio de Dermatología, Instituto Valenciano de Oncología, Valencia, España. celiareq@hotmail.com
Actas Dermo-Sifiliograficas
|May 19, 2009
Summary
Cutaneous epithelioid angiomatous nodules are rare benign vascular growths. Two new cases highlight their typical features, emphasizing a high mitotic index in these epithelioid cell proliferations.
Area of Science:
- Dermatopathology
- Vascular Biology
- Oncology
Background:
- Cutaneous epithelioid angiomatous nodule is a recently described benign vascular proliferation.
- It typically presents as a solitary, rapidly growing, small reddish papulous or nodular lesion on adult skin.
Observation:
- Histopathology shows epithelioid cell proliferation with solid, well-delimited, unilobular growth in the superficial dermis.
- Lesions contain well-defined vessels, inflammatory infiltration, and epithelioid cells with abundant cytoplasm and prominent nucleoli.
- Cellular morphology is uniform without atypia, though mitoses can be present.
Findings:
- Two new cases of cutaneous epithelioid angiomatous nodules are presented.
- Both cases exhibited typical features alongside a notably high mitotic index.
- The cases occurred in a pregnant woman and a young man.
Implications:
- This study contributes to understanding the spectrum of cutaneous vascular proliferations.
- It highlights the importance of considering a high mitotic index in the differential diagnosis.
- Further research may clarify the behavior and potential management of this uncommon entity.
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