Related Experiment Video
Updated: Jun 23, 2026

Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice
Published on: February 18, 2016
Behavioral problems and the occurrence of tobacco, cannabis, and coca paste smoking in Chile: evidence based on
Luis Caris1, Christopher B Anthony, Carlos F Ríos-Bedoya
1University of Chile, Medicine Faculty, Santiago, Chile.
Background:
In this study we estimate suspected links between youthful behavioral problems and smoking of tobacco, cannabis, and coca paste.
Methods:
In the Republic of Chile, school-attending youths were sampled from all 13 regions of the country, with sample size of 46,907 youths from 8th to 12th grades. A Generalized Estimating Equations (GEE) approach to multiple logistic regression was used to address three interdependent response variables, tobacco smoking, cannabis smoking, and coca paste smoking, and to estimate associations.
Results:
Drug-specific adjusted slope estimates indicate that youths at the highest levels of behavioral problems are an estimated 1.1 times more likely to have started smoking tobacco, an estimated 1.6 times more likely to have started cannabis smoking, and an estimated 2.0 times more likely to have started coca paste smoking, as compared to youths at the lowest level of behavioral problems (p<0.001).
Conclusion:
In Chile, there is an association linking behavioral problems with onsets of smoking tobacco and cannabis, as well as coca paste; strength of association is modestly greater for coca paste smoking.
Related Concept Videos
Stress Prevention and Stress Management Techniques IV
Statistical Methods for Analyzing Epidemiological Data
Behavioral Genetics and Its Designs
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One example of...
Conduct Disorder
Cochran's Q Test

