Related Experiment Video
Updated: Jun 23, 2026
07:45
Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis
Published on: February 9, 2021
Influential nutrient in urolithiasis incidence: protein or meat?
Abbas Basiri1, Nasser Shakhssalim, Ali Reza Khoshdel
1Urology and Nephrology Research Center, Shahid Beheshti University, Tehran, Iran.
Summary
High meat consumption, combined with low or high protein diets, is linked to increased urolithiasis incidence. This finding highlights the importance of dietary patterns in kidney stone formation.
Area of Science:
- Urology
- Nephrology
- Nutritional Science
- Epidemiology
Background:
- Urolithiasis, or kidney stones, is a prevalent condition with multifactorial causes.
- Dietary factors are suspected contributors to urolithiasis, but regional variations and specific food components require further investigation.
Purpose of the Study:
- To investigate the association between dietary habits and the incidence of urolithiasis across diverse socioeconomic regions in Iran.
- To identify specific dietary components that correlate with regional urolithiasis prevalence.
Main Methods:
- A population-based, cross-sectional study involving 6,127 urolithiasis cases from 787 imaging centers across 30 provinces in Iran.
- Dietary data from an accredited registry were analyzed using meta-regression models to assess relationships with regional urolithiasis incidence.
Main Results:
- No significant correlation was found between urolithiasis incidence and the intake of calcium, sodium chloride, or dairy products.
- A direct correlation was observed between meat consumption and urolithiasis incidence.
- Protein intake exhibited a significant U-shaped correlation with urolithiasis incidence, with higher rates in both low- and high-protein diet regions.
Conclusions:
- A high proportion of meat consumption, irrespective of total protein intake (low or high), is associated with increased regional urolithiasis incidence.
- Dietary patterns, particularly meat and protein consumption, play a significant role in the geographical distribution of urolithiasis.
Related Concept Videos
01:27Urinary Tract Calculi IV: Nutrition Therapy and Prevention
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
01:28Urinary Tract Calculi I: Introduction
Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
01:28Chronic Kidney Disease III: Interprofessional Care
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
01:30Urinary Tract Calculi III: Medical Management
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
01:28Urinary Tract Calculi V: Nursing Management
AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...