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Updated: Jun 23, 2026

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
Published on: April 26, 2012
Clinical challenges: chemotherapy-induced peripheral neuropathy
1Cancer Pain Program, Division of Hematology-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. j-paice@northwestern.edu
Objectives:
To discuss the challenges associated with treating pain and altered sensations due to chemotherapy-induced peripheral neuropathy (CIPN).
Data Sources:
Published research articles and clinical experience.
Conclusion:
Although there are still great challenges associated with preventing and treating pain and altered sensations due to CIPN, there are preventative strategies and therapeutic options that can certainly improve the quality of life of patients who have cancer.
Implications For Nursing Practice:
Oncology nurses can gain a better understanding of the available pharmacologic and nonpharmacologic strategies that can prevent and reduce pain associated with chemotherapy-induced neuropathy.
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