Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Candidiasis

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...

Regulation of Bacterial Virulence

Regulation of Bacterial Virulence

Pathogenic bacteria employ a range of regulatory mechanisms to modulate the expression of virulence genes in response to environmental and host-derived signals. These mechanisms ensure that virulence factors are expressed only under favorable conditions, thereby optimizing infection and survival strategies.Mechanisms of Virulence RegulationKey regulatory strategies include:Two-Component Systems: These consist of a membrane-bound sensor kinase and a cytoplasmic response regulator. Environmental...

Bacterial Phylum Verrucomicrobiota

Bacterial Phylum Verrucomicrobiota

The phylum Verrucomicrobiota comprises at least four characterized orders, with most species classified within the order Verrucomicrobiotales. Members of this phylum are either aerobic or facultatively aerobic, with the ability to ferment sugars. A notable exception is the genus Methylacidiphilum, which consists of aerobic methanotrophs. Additionally, some Verrucomicrobiota establish symbiotic relationships with protists. These bacteria are widely distributed across various environments,...

Vagina

Vagina

The vaginal canal is a tubular structure averaging about 10 cm in length that acts as the entryway to the female reproductive system and the passageway for menstrual flow and childbirth. The interior walls of the vagina exhibit concentric folds called rugae and are topped by an area known as the fornix, which connects with the protruding cervical portion of the uterus. This canal is comprised of an external fibrous layer, a muscular middle layer, and an inner lining with mucosal rugae, which...

Trichomoniasis

Trichomoniasis

Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.

Microbiota of the Urogenital Tract

Microbiota of the Urogenital Tract

The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Diagnosis of vaginitis-vaginosis by hibridization with DNA strands].

Ginecologia y obstetricia de Mexico·2013

Same author

Evaluation of the BDProbeTec ET system as screening tool in the direct detection of mycobacterium tuberculosis complex in respiratory specimens.

Diagnostic microbiology and infectious disease·2004

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 23, 2026

Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria

Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria

Published on: May 25, 2022

[Bacterial vaginosis].

Iría Jesús De La Calle¹, M Antonia Jesús De La Calle

¹Servicio de Microbiología, Hospital Universitario Puerto Real, Cádiz, España. iria.jesus@uca.es

Medicina Clinica

|May 19, 2009

Summary

Bacterial vaginosis (BV) is a common vaginal condition with complex causes and significant health implications. Despite extensive research, its exact epidemiology and effective long-term treatments remain challenging, leading to high recurrence rates.

Area of Science:

Gynecology
Microbiology
Immunology

Context:

Bacterial vaginosis (BV) is a prevalent condition affecting women's reproductive health.
Despite decades of research, BV remains a controversial entity with inconsistent findings.
Its polymicrobial etiology and high recurrence rates present ongoing research challenges.

Purpose:

To explore the complexities surrounding bacterial vaginosis.
To highlight the unresolved aspects of its epidemiology and treatment.
To underscore the need for continued research into this common infection.

Summary:

Bacterial vaginosis is characterized by increased vaginal discharge and is linked to a higher risk of sexually transmitted diseases.
While not strictly inflammatory, an immune response is present in BV.

More Related Videos

Multiplex Detection of Bacteria in Complex Clinical and Environmental Samples using Oligonucleotide-coupled Fluorescent Microspheres

Multiplex Detection of Bacteria in Complex Clinical and Environmental Samples using Oligonucleotide-coupled Fluorescent Microspheres

Published on: October 23, 2011

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

Related Experiment Videos

Last Updated: Jun 23, 2026

Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria

Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria

Published on: May 25, 2022

Multiplex Detection of Bacteria in Complex Clinical and Environmental Samples using Oligonucleotide-coupled Fluorescent Microspheres

Multiplex Detection of Bacteria in Complex Clinical and Environmental Samples using Oligonucleotide-coupled Fluorescent Microspheres

Published on: October 23, 2011

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

The infection's polymicrobial nature and frequent recurrence post-treatment necessitate further investigation.

Impact:

BV is associated with serious obstetrico-gynecological complications.
Understanding BV is crucial for managing reproductive health and preventing STIs.
Further research may lead to improved diagnostic and therapeutic strategies for bacterial vaginosis.