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Updated: Jun 23, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Fungal postoperative spondylodiscitis due to Scedosporium prolificans
Carolina Garcia-Vidal1, Carmen Cabellos, Josefina Ayats
1Infectious Disease Service, IDIBELL-Hospital Universitary de Bellvitge, University of Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain. carolgv75@hotmail.com
Background Context:
Postoperative fungal spondylodiscitis is a rare infectious disease.
Purpose:
We report the first case of postoperative spondylodiscitis because of Scedosporium prolificans and review postoperative vertebral infection caused by fungi.
Study Design/Setting:
Medline search.
Methods:
Case report and literature review.
Results:
On reviewing the cases of postoperative fungal spondylodiscitis reported so far in the literature, we found eight were caused by mold, and five by yeast. Clinically, the disease presents similar to postoperative vertebral osteomyelitis caused by bacteria, and a high clinical index of suspicion may be required to perform appropriate cultures to establish a diagnosis. Our review revealed a significant number of cases that were cured after surgical debridement and/or antifungal therapy.
Conclusions:
On the basis of this limited assessment, it appears that the clinical course and prognosis of postoperative fungal spondylodiscitis is similar to that reported for postoperative pyogenic spondylodiscitis.
Insights
Postoperative fungal spondylodiscitis, a rare infection, presents similarly to bacterial forms. Early diagnosis and treatment, including surgery and antifungals, are crucial for favorable outcomes.
Area of Science:
- Infectious Diseases
- Mycology
- Neurosurgery
Background:
- Postoperative fungal spondylodiscitis is a rare but serious spinal infection.
- Fungal vertebral infections pose diagnostic and therapeutic challenges.
Observation:
- This study details the first reported case of postoperative spondylodiscitis caused by Scedosporium prolificans.
- A literature review identified eight mold and five yeast-related cases of postoperative fungal spondylodiscitis.
Findings:
- Clinical presentation of fungal spondylodiscitis mimics bacterial vertebral osteomyelitis, necessitating a high index of suspicion for diagnosis.
- Surgical debridement and antifungal therapy demonstrated significant success in treating these infections.
Implications:
- Prompt diagnosis and appropriate management, including surgical intervention and antifungal treatment, are vital for improving patient prognosis.
- The clinical course and prognosis of fungal spondylodiscitis are comparable to those of pyogenic spondylodiscitis.
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