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Membrane flow within the myelin sheath in IDPN neuropathy

A E Blaurock1, M B Genter St Clair, D G Graham

  • 1Department of Physiology, Duke University Medical Center, Durham, North Carolina.

Neuropathology and Applied Neurobiology
|August 1, 1991
PubMed

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Overview
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Action Potential

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Action Potential01:14

Action Potential

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Propagation of Action Potentials

The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
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Diabetic Neuropathy01:22

Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...