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07:27
A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting
Published on: May 16, 2013
Spleen modulation of cytoadherence properties of Plasmodium falciparum
Anjanie Munasinghe1, Manjula Ileperuma, Gayani Premawansa
1Malaria Research Unit, Department of Parasitology, Faculty of Medicine, University of Colombo, Sri Lanka.
Scandinavian Journal of Infectious Diseases
|May 19, 2009
Abstract:
Cytoadherence to CD36 and ICAM-1 and var gene expression of P. falciparum parasites from a splenectomized patient were studied. These parasites lacked cytoadherence and showed expression of a non-coding cDNA sequence. Hence the spleen's modulation of parasite cytoadherence by mechanisms that affect the parasite's surface antigen expression is suggested.
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