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Daily negative mood affects fasting glucose in type 2 diabetes
Marilyn M Skaff1, Joseph T Mullan, David M Almeida
1Department of Family & Medicine, University of California, San Francisco, CA, USA. marilyn.skaff@ucsf.edu
Summary
Negative moods, not positive ones, were linked to higher blood glucose the next day in people with Type 2 diabetes. Blood glucose levels did not appear to influence mood in this 21-day study.
Area of Science:
- Endocrinology
- Psychiatry
- Behavioral Medicine
Background:
- Mood disturbances are common in Type 2 diabetes.
- The bidirectional relationship between mood and glycemic control requires further investigation.
Purpose of the Study:
- To investigate the daily relationship between positive and negative affect and subsequent fasting blood glucose levels in individuals with Type 2 diabetes.
- To determine if blood glucose levels predict subsequent mood states.
Main Methods:
- A 21-day daily diary study was conducted with 206 participants with Type 2 diabetes.
- Participants completed daily mood assessments via telephone and self-monitored fasting blood glucose.
- HbA1c levels and demographic data were collected at baseline.
Main Results:
- Multilevel analyses indicated a significant association between higher negative affect on one day and increased fasting blood glucose on the following day.
- No significant relationship was found between positive affect and subsequent blood glucose levels.
- Blood glucose levels did not predict subsequent positive or negative affect.
Conclusions:
- Negative affect, but not positive affect, precedes and may influence blood glucose levels in Type 2 diabetes.
- The findings suggest a unidirectional relationship where mood impacts glycemic control, rather than vice versa.
- Understanding this mood-glucose link may inform interventions for improved diabetes management.
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