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Platelet interactions as therapeutic targets for prevention of atherothrombosis

Jan Smid1, Ruediger Braun-Dullaeus, Meinrad Gawaz

  • 1Universitätsklinik für Kardiologie, Angiologie & Pneumologie, Universitätsklinikum Magdeburg, Leipziger Strasse 44, Magdeburg 39120, Germany. jan.smid@med.ovgu.de

Future Cardiology
|May 20, 2009
PubMed

Physiologically, platelets perform important tasks to maintain the homeostasis of the vascular wall and the surrounding environment. In pathologic conditions, however, platelets contribute to the formation of atherosclerotic plaques as well as to atherothrombotic events (i.e., acute myocardial infarction). This review aims to elucidate the role of platelets in atherogenesis and atherothrombosis and to provide an insight into current and future strategies for platelet inhibition.

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